CBCT Study

Purpose

The purpose of this study is to evaluate if the practice of Cognitive-based compassion training, a meditative practice based on Buddhist teachings, can decrease inflammation in people living with HIV based on certain chemical markers from a patient's blood. The study will also evaluate what effects the practice has on self-perceived levels of stress. To our knowledge, there have been no successful interventions that have been able to control the level of inflammation in PLHIV beyond being on antiviral medications. This study may help lay the groundwork in looking for new and alternative methods of helping recover the immune system function in PLHIV.

Procedure

Participants in the study will go through an 8 week course previously designed by the Emory-Tibet Partnership. The participants will have blood samples drawn before the course begins and then again after the completion of the course to compare changes in blood markers of inflammation. In addition, participants will be asked to fill several psychological self-assessments before and after the course, as well as a survey regarding how much of the techniques they learned are actually practiced outside of the class. The results from these patients will be compared to another group of patients who will also undergo classes focused on general health and healthy lifestyles.

Who can participate?

We are seeking adults living with HIV-1 infection who have been on continuous ART for a minimum of 12 months and are followed longitudinally for their HIV healthcare at the IDP and meet criteria for immunological non-responsiveness as defined by adherence to ART and CD4 count <350 cells/μL despite complete virologic suppression (> 2 pVL below the limit of detection including the most recent pVL prior to enrollment).

To learn more contact

Mehul Tejani at mehul.navin.tejani@emory.edu